Despaigne debuted for the Padres in 2014 as a starter and then split last season between the rotation and the bullpen. Overall in two seasons as a big leaguer he has a 4.74 ERA in 222 innings, managing just 5.4 strikeouts per nine frames.
Given his low strikeout rate and relatively high home run total leaving a pitcher-friendly ballpark and going from the NL to the AL figures to be particularly rough on Despaigne, although it’s also possible the 29-year-old opens the season in the minors.
Cosme was a 17th-round draft pick in 2014 and spent last season pitching at low Single-A, posting a 4.74 ERA and 53/18 K/BB ratio in 57 innings as a starter. He’s considered a marginal prospect.