Angel Pagan re-injured his lower back

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Angel Pagan had been hoping to be activated from the disabled list on Tuesday for the Giants’ series opener against the visiting Cardinals, but Andrew Baggarly of CSNBayArea.com reports that the center fielder experienced a setback involving the bulging disc in his lower back Monday while running.

Pagan will visit back specialist Dr. Robert Watkins on Wednesday afternoon in Los Angeles for an exact diagnosis and recommendation on treatment. Pagan expects to avoid season-ending surgery, but his recovery timetable at this point is very much up in the air.

The bulging disc is pinching his sciatica nerve and causing shooting pain down his leg.

Pagan was hitting .307/.356/.411 with 37 runs scored in 63 games this season before the injury.

Juan Perez is starting in center field and batting leadoff on Tuesday night versus St. Louis.

Report: José Ramírez diagnosed with knee contusion

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Indians third baseman José Ramírez had to be carted off the field in the top of the third inning of Sunday afternoon’s Cactus League game agaisnt the White Sox. Ramírez fouled a pitch off of his leg during an at-bat against pitcher Sean Nolin.

MLB.com’s Mandy Bell reports that Ramírez was diagnosed with a left knee contusion after he was taken for X-rays. The X-rays were negative, per ESPN’s Jeff Passan.

Ramírez, 26, finished third in AL MVP Award voting last season, batting .270/.387/.552 with 39 home runs, 105 RBI, 110 runs scored, and 34 stolen bases across 698 plate appearances. He was worth 7.9 Wins Above Replacement, according to Baseball Reference. If Ramírez lands on the injured list, that would obviously be a huge loss for the Indians, despite being the overwhelming favorites in the AL Central entering the season.

The Indians will already start the season without second baseman Jason Kipnis and shortstop Francisco Lindor, though both are expected to return before the end of April. The infield is in rough shape at the moment.