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Ryan Braun’s suspension may be the easiest of them all: looking at the next Biogenesis targets

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Ryan Braun’s suspension was first and, as the alleged public enemy number one — or two — of Major League Baseball, may eventually be seen as the most significant.  But at the moment it sort of seems like small potatoes, all things considered.

Why? Because the Brewers season was already effectively over and it will all end for Braun and his team after the season ends.  There are other Biogenesis suspensions, however, which will have a much bigger and potentially longer-lasting impact.

The ones to watch: Bartolo Colon, Jhonny Peralta, Nelson Cruz, all of whom are reported to be in Major League’s sights, all of whom are playing for playoff contenders. Depending on what the league makes of Gio Gonzalez’s passing mention on the list, the Nationals could be affected too. Colon, depending on how the league views his inclusion vis-a-vis last year’s positive drug test, could be facing second offender discipline.

Do these players pull a Ryan Braun and take their medicine now? If so, they will deprive their teammates of key cogs just as the playoff stretch drive gets underway. Do they appeal? If so, they risk greater penalties, one assumes, legal costs and the likelihood that any discipline ultimately stretches into next year.

Can the A’s replace Colon in the rotation? Who plays shortstop for the Tigers if Peralta is gone? Nelson Cruz hit a big homer for the Rangers last night. Who is their deep threat with him gone?

Those are all less-sexy topics than bad boy Ryan Braun or badder boy Alex Rodriguez getting popped. But they have far greater actual baseball implications.

Report: Phillies want a top-five prospect for Jeremy Hellickson

PHILADELPHIA, PA - JULY 20: Starting pitcher Jeremy Hellickson #58 of the Philadelphia Phillies throws a pitch in the second inning during a game against the Miami Marlins at Citizens Bank Park on July 20, 2016 in Philadelphia, Pennsylvania. (Photo by Hunter Martin/Getty Images)
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Starter Jeremy Hellickson has become the Phillies’ most enticing trade chip as he’s put together a solid month of July. After shutting out the Marlins on one hit and one walk over six innings on Monday, the right-hander lowered his July ERA to 1.97 and his overall ERA to 3.65. As a result, the Phillies are telling teams they want a top-five prospect to part with Hellickson, per ESPN’s Jayson Stark.

Obviously, a top-five prospect means something different if you’re the Marlins as opposed to the Rangers. And the Phillies’ price point for Hellickson isn’t likely to stay that high, but GM Matt Klentak is setting a lofty starting point so that the return might end up being higher than market value.

ESPN’s Buster Olney speculates that the Phillies could end up holding onto Hellickson and giving him a qualifying offer after the season. He notes that the Phillies have only $25 million tied up for the 2017 season, so they could afford to pay Hellickson in excess of $16 million if he were to accept.

Video: Matt Cain launches a three-run home run

SAN FRANCISCO, CA - JULY 26: Matt Cain #18 of the San Francisco Giants hits a three run home run against the Cincinnati Reds during the second inning at AT&T Park on July 26, 2016 in San Francisco, California.  (Photo by Jason O. Watson/Getty Images)
Jason O. Watson/Getty Images
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Madison Bumgarner isn’t the only Giants pitcher who can rake. Matt Cain crushed a three-run home run during Tuesday’s game against the Giants.

Cain stepped to the plate with runners on the corner and one out against Reds starter Cody Reed in the bottom of the second inning. Reed threw a 1-1 fastball down the middle and Cain hit it about 20 rows back in the left field seats.

It’s Cain’s first homer of the season, his first since 2012, and the seventh of his 12-year career. He still has some work to catch up to Bumgarner, who has two homers this year and 13 in his career.

On the pitching side of things, Cain got the win against the Reds on Tuesday night, giving up four runs on six hits and a walk with four strikeouts in 5 1/3 innings. He currently holds an ugly 5.95 ERA.