Jeff Karstens scratched Sunday due to shoulder discomfort

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Some bad news this morning out of Pirates camp.

According to beat writer Michael Sanserino of the Pittsburgh Post-Gazette, right-handed starter Jeff Karstens has been scratched from his scheduled Grapefruit League outing Sunday against the Orioles because of “continuing shoulder discomfort.”

Karstens reported feeling soreness in his right shoulder on February 19 — after one of his first throwing sessions of the spring. It was manageable for a while but is now causing him great discomfort. He will open the 2013 regular season on the 15-day disabled list, without a mapped-out return timetable.

Karstens posted a 3.97 ERA and 1.15 WHIP in 90 2/3 innings last season while fighting hip and shoulder injuries. Jeff Locke, Jonathan Sanchez, Kyle McPherson and Jeanmar Gomez are fighting for his spot.

Sean Manaea has a no-hitter through eight innings

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UPDATE (11:06 PM ET): Manaea is through eight innings of his no-hitter. He caught Rafael Devers looking, then induced a pop-up to retire Sandy Leon and whiffed Jackie Bradley Jr. to end the inning. He’s at 95 pitches and a career-high 10 strikeouts entering the ninth.

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Athletics southpaw Sean Manaea has no-hit the Red Sox through seven innings of Saturday’s game. Any thought of a perfect game was banished in the first at-bat, when Mookie Betts drew a leadoff six-pitch walk to open the first inning. From there, Manaea held the Sox to just three total baserunners through the first seven innings.

Andrew Benintendi tried to break up the no-no in the sixth inning, collecting an infield hit for what appeared to be the Red Sox’ first hit of the evening. Upon further review, however, the hit was reversed after Benintendi incurred a batter interference call for running outside the baseline.

Manaea is currently working with a three-run lead thanks to RBI doubles from Jed Lowrie and Stephen Piscotty and Marcus Semien‘s solo shot off of Chris Sale in the fifth. He’s racked up eight strikeouts against 23 batters so far.

If Manaea sees the no-hitter through to completion — as seems entirely possible, given that his pitch count is resting at 84 entering the eighth — he’ll be the first A’s pitcher to toss a no-no since Dallas Braden’s perfect game against the Rays eight years ago. The last time the Red Sox were on the losing end of a no-hitter, meanwhile, was back in 1993 against the Mariners’ Chris Bosio.