Ryan Madson had a setback in his return from Tommy John surgery

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When the Angels signed Ryan Madson to be their new closer they seemed pretty confident that he’d be ready for Opening Day after missing all of last season following Tommy John elbow surgery, but suddenly that’s looking like a long shot.

Mike DiGiovanna of the Los Angeles Times reports that Madson experienced a setback in his recovery when he had elbow soreness during a mound session on February 1 and hasn’t thrown since then.

Madson beginning the season on the disabled list would open the door for Ernesto Frieri to serve as closer. Madson’s one-year deal with the Angels is worth $3.5 million in guaranteed money, plus another $3.5 million in potential incentives based on games finished and days on the active roster.

Remember when the Phillies were on the verge of re-signing Madson to a four-year, $44 million contract last offseason and, at least according to agent Scott Boras, had agreed to the deal? Does wriggling out of those negotiations now count toward the “Ruben Amaro Jr. is a ninja” evidence?

Mike Moustakas sets Royals single-season record with 37th home run

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Royals third baseman Mike Moustakas belted his 37th home run on Wednesday evening, setting a new club record for homers in a single season. Moustakas had been tied with Steve Balboni, who hit 36 home runs in 1985.

The home run came on a 2-0, 82 MPH slider from Blue Jays reliever Carlos Ramirez, boosting the Royals’ lead to 13-0 in the top of the sixth inning.

Moustakas, 29, entered the night batting .271/.313/.523 with 82 RBI and 71 runs scored in 560 plate appearances.

Chris Sale records his 300th strikeout this season

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Red Sox starter Chris Sale recorded his 300th strikeout of the 2017 season on Wednesday night against the Orioles. The momentous occasion occurred with two outs in the eighth inning. Facing Ryan Flaherty, Sale threw a slider that caught the strike zone low and inside for called strike three.

Sale and Clayton Kershaw (2015) are the only pitchers to strikeout 300-plus batters in a season in the last 15 years. Curt Schilling and Randy Johnson accomplished the feat in 2002, and Johnson also did it in 2001 and 2000. Pedro Martinez had been the only other Red Sox pitcher to have a 300-strikeout season.

Through eight scoreless innings, Sale limited the Orioles to four hits with no walks and 13 strikeouts. The Red Sox offense gave him plenty of run support. Mookie Betts and Devin Marrero each hit two-run home runs in the fourth. Hanley Ramirez added a two-run double in the sixth and Dustin Pedroia hit a two-run double of his own in the eighth to make it 8-0.