Johan Santana has a 6.54 ERA since his no-hitter

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Johan Santana’s struggles continued tonight against the Dodgers, as he was chased after being knocked around for six runs over just three innings. It matched the second-shortest start of his career.

Santana gave up seven hits in all, including a two-run homer to Matt Kemp in the first inning and a two-run homer to Luis Cruz in the third. He walked three and struck out three and threw 45 out of 72 pitches for strikes.

Santana has now allowed 19 runs over his past three starts and six runs or more in each of them. The southpaw is just the third Mets’ pitcher to give up six runs or more in three straight starts, joining Pedro Astacio and Bobby Jones. He’s the fourth pitcher in the majors to do it this season, along with Joe Blanton, Bruce Chen and Mike Minor.

Santana, who missed all of last season while rehabbing his surgically-repaired left shoulder, now has a 3.98 ERA in 110 1/3 innings through 19 starts this season. This includes an ugly 6.54 ERA in eight starts since he threw a career-high 134 pitches in his no-hitter against the Cardinals back on June 1. Perhaps he was due to hit a wall at some point anyway, but given how much he has struggled recently, it’s hard not to look back to his workload from that historic evening in Queens.

Dodgers designate Sergio Romo for assignment

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The Dodgers announced on Thursday that the club activated pitcher Grant Dayton from the 10-day disabled list and designated pitcher Sergio Romo for assignment.

Dayton, 29, went on the disabled list earlier this month with neck stiffness. He’ll resume with a 3.63 ERA and a 20/12 K/BB ratio in 22 1/3 innings.

Romo, 34, signed a one-year, $3 million deal with the Dodgers in February. It didn’t really work out, as the right-hander posted a 6.12 ERA with a 31/12 K/BB ratio in 25 innings. His peripherals are still decent, so it wouldn’t be surprising if a team in need of a bullpen arm makes a deal with the Dodgers within the week.

Nate Karns underwent season-ending surgery for thoracic outlet syndrome

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MLB.com’s Jeffrey Flanagan reports that Royals pitcher Nate Karns underwent surgery for thoracic outlet syndrome on Wednesday. He’s expected to be ready for spring training next year. Karns went on the disabled list in May with an elbow injury and didn’t make much progress.

The Royals acquired Karns from the Mariners in January in exchange for outfielder Jarrod Dyson. Over eight starts and one relief appearance, the 29-year-old right-hander compiled a 4.17 ERA and a 51/13 K/BB ratio in 45 1/3 innings.

Karns will enter his first of three years of arbitration eligibility after the season, so he’ll be under the Royals’ control through 2020.