Johan Santana is struggling since his no-hitter

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Did the 134 pitches take a toll? After getting lit up by the Yankees last week, Johan Santana gave up four runs in five-plus innings Thursday versus the Rays in his second start since his no-hitter.

The 134 pitches Santana threw in shutting down the Cardinals were a career high for the left-hander, who was handled carefully during the first two months in his first season back from shoulder surgery. Pitching on six days’ rest last Friday, he gave up six runs and four homers in five innings in a loss to the Yankees. Today, working on five days’ rest, he got a win, but he allowed four runs in five-plus innings.

It actually should have been worse. Santana loaded the bases with no outs in the sixth, giving up a single to Hideki Matsui, a double to Ben Zobrist and a walk to Matt Joyce. Jon Rauch took over and managed to strand all three runners by getting two strikeouts and then a groundout.

Santana threw just 51 of his 95 pitches for strikes in this one. He issued four walks, his second highest total of the season (he walked five in the no-hitter).

Santana’s ERA has jumped from 2.38 to 3.23 since the no-no and would be higher if not for Rauch’s effort. The Mets have to be hoping its an aberration, not a trend. Santana and R.A. Dickey have been an outstanding one-two punch so far, but Santana needs to return to May form to keep that up.

Report: Twins interested in Wade Miley

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Free agent left-hander Wade Miley is among several offseason targets for the Twins, according to a report from Darren Wolfson of KSTP. Miley’s $12 million option was declined by the Orioles back in November, and while he’s expected to attract another major league deal in 2018, he hasn’t exactly been highly sought after this offseason.

The 31-year-old lefty finished his second campaign with the Orioles in 2017, producing an 8-15 record in 32 starts and ranking second-to-last among all AL starters with a 5.61 ERA, 5.3 BB/9 and 8.1 SO/9 in 157 1/3 innings. Even taking Miley’s undeniable durability into account — he remained healthy for the bulk of the season and completed his sixth straight year with 30+ starts — his declining value and career-worst numbers may lower his price tag as the 2018 season approaches.

Wolfson notes that the Twins have engaged in “regular dialogue” with Miley’s agent this winter, but he’s far from the only starting pitcher they have their eye on. Right-handers Yu Darvish, Lance Lynn, Alex Cobb and Chris Tillman are still on their radar, among several others, and club owner Jim Pohlad said Saturday that he was “totally on board” with the idea of signing a big-name free agent like Darvish or another available starter. “There are some interesting names and some interesting opportunities there,” Pohlad told a crowd at TwinsFest. “I’m as intrigued by it as anybody and attracted to it as anybody.”