I presume it’s rare. I couldn’t think of anyone else who has done it, and I’m not exactly sure how to research it without sifting through 100 box scores I don’t feel like sifting through right now. But C.J. Wilson’s loss last night means that in 2011 he lost (a) the All-Star Game; (b) a Division Series game; (c) a League Championship Series game; and (d) a World Series game.
Maybe there are several who did it. I don’t know. But usually you don’t get to play in all three rounds of the playoffs if your ace — and he has to be your ace, does he not, if he pitched in the All-Star Game — loses lots in the playoffs.
Significance: zero. Just kind of neat.